Segments

Our Business Segments

Products, R&D and Fermentation services

The Group divides its business activities into three operating segments plus a holding company. The level of innovation and scalability is reflected in these three segments. Each of the three operating segments has a clearly defined business model. 

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BioProducts
Products business with specialized enzymes and other proteins
BioProducts

Enzymes & proteins

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The BioProducts segment comprises the product business with specialized enzymes and other proteins. The BRAIN Biotech Group operates fermentation plants in the United Kingdom and production facilities in continental Europe and the USA to manufacture these products. The legal entity for the product business is the wholly owned subsidiary Biocatalysts Ltd. in Cardiff, Wales, United Kingdom.

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BioScience
R&D Services for customized enzyme and bioprocess solutions
Enzyme technology, producer strains & bioprocesses

Customized and for special applications

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The BioScience segment comprises research-intensive, custom solutions based on enzyme technology, strain development, bioprocess development and natural product screening. We are the partner of choice when industry is looking for innovative biobased solutions.

Our innovative strength is based on a comprehensive portfolio of biotechnological and analytical methods as well as an intensive scientific, interdisciplinary and application-oriented exchange within the three technology units at the Zwingenberg site. Combined with an agile way of working and a close exchange with colleagues at our production sites, the requirements of our customers lead to innovative solutions for their processes or products.

Development of new enzyme products

Through our R&D activities at the Zwingenberg site, we are continuously expanding our product portfolio with innovative specialty enzymes. The BRAIN Biotech AG bioarchive contains approximately 53,000 comprehensively characterized microorganisms, chassis microorganism strains for the development of production organisms and genetic libraries with new enzymes and metabolic pathways. The collection is being expanded in ongoing projects and allows the identification of previously uncharacterized enzymes and new access to previously uncultivable microorganisms.

Expansion of substance libraries

The Potsdam site has a collection of pure natural compounds and semi-synthetic compounds based on natural building blocks. The collection also includes small molecules. These can be the starting point for screening, e.g. for drug candidates for pharmaceutical applications.

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BioIncubator
R&D pipeline with promising solutions

Examples of successful high-intensity research projects

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The BioIncubator is our R&D pipeline of proprietary and partnered projects with high value creation potential. The research-intensive projects are driven forward at the Zwingenberg and Potsdam research sites.

Examples:

  • In-house development of proprietary CRISPR-Cas nucleases for genome editing in customer projects
  • Aurase® enzyme for wound healing: successful completion of the Phase 2a clinical trial by partner SolasCure
  • Biological gold recovery from e-waste: further development by an industrial partner.
  • Identification and characterization of an active substance for the treatment of hereditary angioedema (HAE): out-licensing and clinical development by Pharvaris N.V.