Biocatalysts: Scaling of a special enzyme for a large pharmaceutical company successfully completed
Powerful new chromatography system used for the first time
Biocatalysts Ltd has successfully completed the large-scale production of a special ligase for a major pharmaceutical company. A new state-of-the-art chromatography system, which the enzyme company installed at its Cardiff site last year, was used to purify the enzyme molecules after the fermentation process.
Chromatography is used to separate and concentrate the desired product from other soluble substances to remove any remaining impurities and achieve high product purity.
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High purity enzymes, such as ligases and polymerases are increasingly being used in pharmaceutical and larger scale manufacturing applications. The successful scale up of this speciality ligase represents one of a number of current projects at our Cardiff site for the pharmaceutical and life sciences markets using our latest advanced purification technology.
- VP of Food & Pharmaceuticals at Biocatalysts Ltd
